![]() ![]() Here, we investigated the effects of borax, a boron compound, on the ferroptosis signaling pathway mediated by PCBP1 and autophagy. PCBP1 is also known to regulate autophagy, but the role of PCBP1 in ferroptosis, iron-dependent cell death pathway, remains unrevealed in GBM cells. Poly(rC)-binding protein 1 (PCBP1) is a cytosolic iron chaperone with diverse functions. Unfortunately, there are currently no curative treatments for GBM. ![]() ![]() Glioblastoma (GBM) is classified as a stage-IV glioma. ![]()
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